You can access the Preferences Dialog with the menu item View->Preferences. You can choose some decoration options, like whether to show icons in menus or not, but also something more effective. For example, you can modify the number of buttons in the Main Palette. If you type a value of 15 or 30, you get a long toolbar-like Main Palette. You can also choose the default path where you save wxGlade files or generate source code.

Another useful option is to enable a default border of 3 around some widgets. In many cases this can be useful to have set.

You need to restart wxGlade for changes to take effect.